TracVac funded article published in NPJ Vaccines
The article "A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars" by members of the TracVac consortium was published in NPJ Vaccines on April 19th 2021.
A major goal in the TracVac project is to generate a vaccine that protect against the bacterial strains causing ocular Chlamydia trachomatis (C.t) infections. C.t. infections cause several human diseases, including trachoma, the leading cause of blindness as a result of infection, and a spectrum of diseases caused by sexually transmitted infections, among them infertility, ectopic pregnancy, and chronic pelvic pain. This article focused on developing a vaccine construct with the ability to induce broadly neutralizing antibodies against C/C-related complex serovars. The vaccine proved to be highly immunogenic and protective against both ocular and genital strains.
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